Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4142583 | 0.89 | ALDH1A1 (0.51) | POLBALDH1A1SLC2A1 | |
| SCHEMBL92331 | 0.88 | L3MBTL1 (0.56) | L3MBTL1KMT2ACYP2C9CYP2C19POLB | |
| Bromide SCHEMBL28426487 | 0.87 | L3MBTL1 (0.54) | L3MBTL1KMT2ACYP2C9CYP2C19POLB | |
| Hydrochloric Acid SCHEMBL4768580 | 0.87 | L3MBTL1 (0.54) | L3MBTL1KMT2ACYP2C9CYP2C19POLB | |
| Trifluoroacetic Acid SCHEMBL6792862 | 0.86 | MMP13 (0.45) | KMT2ASIGMAR1PKMMEN1 | |
| Trifluoroacetic Acid SCHEMBL27526745 | 0.84 | ITGB3 (0.42) | SLC2A1 | |
| Trifluoroacetic Acid SCHEMBL4061499 | 0.84 | ITGB3 (0.42) | SLC2A1 | |
| Trifluoroacetic Acid SCHEMBL4397854 | 0.83 | F10 (0.46) | — | |
| SCHEMBL10765650 | 0.81 | L3MBTL1 (0.59) | L3MBTL1KMT2ACYP2C9CYP2C19POLB | |
| Trifluoroacetic Acid SCHEMBL71716 | 0.80 | HRH4 (0.37) | CYP2C9ALDH1A1LMNAPKMBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563092-B | 2-phenylimidazo [4,5-B ] pyridin-7-amine derivatives useful as inhibitors of the activity of the mammalian tyrosine kinase ROR1 | 坎塞拉有限公司 | 2021-09-14 | — | — | CN | disclosed |