Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30064948 | 0.82 | ALDH1A1 (0.41) | PIN1L3MBTL1ALDH1A1TDP1KMT2A | |
| SCHEMBL3249094 | 0.82 | ALDH1A1 (0.41) | PIN1L3MBTL1ALDH1A1TDP1KMT2A | |
| SCHEMBL22604844 | 0.81 | MERTK (0.53) | PIN1ALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL22604807 | 0.79 | PIN1 (0.58) | PIN1ALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL29066613 | 0.78 | HPGD (0.59) | PIN1L3MBTL1ALDH1A1TDP1KMT2A | |
| SCHEMBL22588351 | 0.75 | L3MBTL1 (0.55) | PIN1L3MBTL1ALDH1A1TDP1KMT2A | |
| SCHEMBL1340893 | 0.74 | ALDH1A1 (0.80) | PIN1L3MBTL1ALDH1A1TDP1KMT2A | |
| SCHEMBL22604840 | 0.73 | PIN1 (0.61) | PIN1L3MBTL1ALDH1A1TDP1KMT2A | |
| SCHEMBL1340625 | 0.73 | L3MBTL1 (1.00) | PIN1L3MBTL1ALDH1A1TDP1KMT2A | |
| SCHEMBL1748457 | 0.73 | DHPS (0.50) | PIN1L3MBTL1ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113924298-A | Compounds comprising N-methyl-2-pyridone and pharmaceutically acceptable salts | 邓迪大学 | 2022-01-11 | — | — | CN | disclosed |