Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28796938 | 0.75 | ROCK2 (0.36) | ROCK2APPLMNA | |
| SCHEMBL26683536 | 0.74 | ROCK2 (0.37) | ROCK2APPPTGDR2PTGDRLMNA | |
| SCHEMBL29073846 | 0.70 | PTGS2 (0.41) | ROCK2PTGDR2PTGDR | |
| SCHEMBL29470914 | 0.69 | ROCK2 (0.47) | ROCK2EPHX2 | |
| SCHEMBL1013646 | 0.69 | ROCK2 (0.47) | ROCK2EPHX2 | |
| SCHEMBL29241242 | 0.68 | ROCK2 (0.46) | ROCK2SMN1; SMN2NPSR1NPC1LMNA | |
| SCHEMBL28253756 | 0.68 | ROCK2 (0.43) | ROCK2SMN1; SMN2NPSR1NPC1LMNA | |
| SCHEMBL28420979 | 0.68 | POLB (0.36) | ROCK2NPSR1RAB9AHPGD | |
| SCHEMBL30576990 | 0.68 | POLB (0.36) | ROCK2NPSR1RAB9AHPGD | |
| SCHEMBL6883018 | 0.68 | SMN1; SMN2 (0.38) | APPPTGDR2PTGDRSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117586148-A | Synthesis method of perfluorinated nitrile compound | 天津市长芦化工新材料有限公司 | 2024-02-23 | — | — | CN | claimed |
| CN-115850254-A | Synthetic method of sulfuryl pyraflufen | 山东润博生物科技有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-114196018-A | Thiazolothiazolyl polymer and preparation method and application thereof | 福州大学 | 2022-03-18 | — | — | CN | claimed |
| CN-107540725-B | Water-soluble tanshinone IIA derivative and preparation and application thereof | 孙青� | 2020-04-07 | — | — | CN | claimed |
| CN-115850254-B | Synthesis method of pyrifos | 山东润博生物科技有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-115536650-B | Synthesis method of topiramate intermediate | 山东润博生物科技有限公司 | 2024-06-14 | — | — | CN | disclosed |