Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAT2A | P31153 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | PTPRF | P10586 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30576990 | 0.97 | POLB (0.36) | POLBCASP3SENP7SENP6HPGD | |
| SCHEMBL27007938 | 0.90 | HPGD (0.33) | POLBCASP3SENP7SENP6HPGD | |
| SCHEMBL29015609 | 0.84 | — | — | |
| Phosphine SCHEMBL1505614 | 0.83 | POLB (0.34) | POLBCASP3SENP7SENP6HPGD | |
| SCHEMBL30788667 | 0.79 | RXRA (0.40) | HPGDGAAMEN1RAB9AKMT2A | |
| SCHEMBL29644614 | 0.78 | PTPN1 (0.38) | PTPN1PTPRCPTPRFCDC25B | |
| SCHEMBL30731374 | 0.73 | LMNA (0.43) | CDC25BMAPTALDH1A1 | |
| SCHEMBL30357793 | 0.73 | PTPN1 (0.34) | PTPN1PTPRCPTPRFCDC25B | |
| SCHEMBL1408109 | 0.72 | HPGD (0.44) | POLBCASP3SENP7SENP6HPGD | |
| SCHEMBL7712240 | 0.71 | LMNA (0.42) | CDC25BMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820209-A | Preparation method of 4- [3- (cyclopropylmethoxy) -4- (difluoromethoxy) phenethyl ] pyridin-2-ol | 中国医学科学院药物研究所 | 2024-04-05 | — | — | CN | claimed |
| CN-112778267-A | Thiophene-3 (2H) -ketone compound and synthetic method thereof | 华东师范大学 | 2021-05-11 | — | — | CN | claimed |
| CN-107814757-B | Method for synthesizing polysubstituted pyrrole derivative | 南京医科大学康达学院 | 2021-02-05 | — | — | CN | claimed |
| CN-110128323-B | Fluorenocarbazole derivative, and preparation method and application thereof | 武汉尚赛光电科技有限公司 | 2021-02-02 | — | — | CN | claimed |
| CN-117820209-A | Preparation method of 4- [3- (cyclopropylmethoxy) -4- (difluoromethoxy) phenethyl ] pyridin-2-ol | 中国医学科学院药物研究所 | 2024-04-05 | — | — | CN | disclosed |
| CN-117500796-A | Sulfinimides and application thereof | 南京明德新药研发有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116848122-A | Plasmin inhibitor, preparation method and application thereof | 赛诺哈勃药业（成都）有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-115745960-A | Quinolinone amide-containing compound, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2023-03-07 | — | — | CN | disclosed |
| CN-115589759-A | Exciplex and organic electroluminescent element | 常州强力昱镭光电材料有限公司 | 2023-01-10 | — | — | CN | disclosed |
| CN-114853766-A | Carbazole fused ring substituted triazine compound and application thereof | 江苏三月科技股份有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-114835697-A | Compound containing triazine and phenanthrene structures and application thereof | 江苏三月科技股份有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-113087649-B | Preparation method of dihydropyrrolone derivative | 南京医科大学康达学院 | 2022-07-12 | — | — | CN | disclosed |
| CN-111943820-A | Method for simply and efficiently synthesizing alpha, beta-unsaturated aldehyde without synthesis gas | 四川大学 | 2020-11-17 | — | — | CN | disclosed |
| CN-111848631-A | Pyrrolo [2,3-d ] pyrimidine derivative targeting EGFR mutation and preparation method and application thereof | 四川大学华西医院 | 2020-10-30 | — | — | CN | disclosed |
| CN-111825537-A | Method for efficiently synthesizing alpha, beta-unsaturated aldehyde without synthesis gas | 四川大学 | 2020-10-27 | — | — | CN | disclosed |
| CN-111825658-A | Novel EGFR (epidermal growth factor receptor) triple-mutation inhibitor and application thereof | 华东理工大学 | 2020-10-27 | — | — | CN | disclosed |
| CN-111699175-A | Prostacyclin receptor agonists | 南京明德新药研发有限公司 | 2020-09-22 | — | — | CN | disclosed |
| CN-111630029-A | Compound as immunomodulator and preparation method and application thereof | 上海济煜医药科技有限公司 | 2020-09-04 | — | — | CN | disclosed |
| CN-111423453-A | Organic electroluminescent material with seven-membered heterocycle as main body and application thereof | 烟台九目化学股份有限公司 | 2020-07-17 | — | — | CN | disclosed |
| CN-111349084-A | Aminopyrimidines useful for inhibiting protein kinase activity | 深圳市塔吉瑞生物医药有限公司 | 2020-06-30 | — | — | CN | disclosed |