Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | PLAA | Q9Y263 | 2/20 | 0.45 |
| ▸ | ALPG | P10696 | 3/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 2/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MYLK | Q15746 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13031578 | 0.83 | ALDH1A1 (0.40) | POLBNPC1ALDH1A1MAPT | |
| SCHEMBL1774579 | 0.83 | MAPT (0.47) | KMT2AMEN1NPC1MAPT | |
| Hydrochloric Acid SCHEMBL1774577 | 0.82 | MAPT (0.46) | KMT2AMEN1NPC1MAPT | |
| SCHEMBL28710511 | 0.82 | POLB (0.51) | KMT2AMEN1PLAAALPGNOS1 | |
| SCHEMBL1593910 | 0.81 | SMN1; SMN2 (0.55) | POLBNPC1ALDH1A1MAPT | |
| SCHEMBL18839661 | 0.81 | L3MBTL1 (0.45) | KMT2AMEN1NPC1HTTALDH1A1 | |
| SCHEMBL30554042 | 0.79 | KDM4E (0.40) | NPC1ALDH1A1MAPT | |
| SCHEMBL27001672 | 0.79 | POLB (0.49) | KMT2AMEN1PLAAALPGNOS1 | |
| SCHEMBL4926204 | 0.79 | NOS1 (0.66) | KMT2AMEN1PLAAALPGNOS1 | |
| SCHEMBL12706154 | 0.78 | LPO (0.42) | KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114230522-A | Imidazole-2-carboxylic acid metal beta-lactamase inhibitor and preparation method and application thereof | 四川大学 | 2022-03-25 | — | — | CN | disclosed |