Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Trifluoromethanesulfonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.37 |
| ▸ | ACHE | P22303 | 7/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL29171769 | 0.94 | KCNH2 (0.37) | KCNH2ACHEGPR3ALDH1A1TSHR | |
| Trifluoromethanesulfonic Acid SCHEMBL28255383 | 0.94 | KCNH2 (0.37) | KCNH2ACHEGPR3ALDH1A1TSHR | |
| Trifluoromethanesulfonic Acid SCHEMBL28553920 | 0.82 | ALDH1A1 (0.48) | KCNH2ACHEGPR3ALDH1A1 | |
| Trifluoromethanesulfonic Acid SCHEMBL29893713 | 0.82 | CA1 (0.44) | KCNH2ACHEGPR3ALDH1A1TSHR | |
| Trifluoromethanesulfonic Acid SCHEMBL17213 | 0.82 | — | — | |
| Trifluoromethanesulfonic Acid SCHEMBL1318399 | 0.82 | CA1 (0.44) | KCNH2ACHEGPR3ALDH1A1TSHR | |
| Trifluoromethanesulfonic Acid SCHEMBL4815937 | 0.82 | CA1 (0.44) | KCNH2ACHEGPR3ALDH1A1TSHR | |
| Trifluoromethanesulfonic Acid SCHEMBL1350592 | 0.80 | GPR3 (0.35) | GPR3ALDH1A1TSHRCA1CA2 | |
| Trifluoromethanesulfonic Acid SCHEMBL31355571 | 0.80 | ACHE (0.36) | KCNH2ACHEGPR3ALDH1A1TSHR | |
| Trifluoromethanesulfonic Acid SCHEMBL15667318 | 0.80 | KCNH2 (0.38) | KCNH2ACHEGPR3CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108232085-B | Polyion liquid coated bacterial cellulose membrane and preparation method thereof | 上海恩捷新材料科技有限公司 | 2022-03-01 | — | — | CN | disclosed |