⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260308 | 0.88 | — | — | |
| SCHEMBL78111 | 0.85 | ALDH1A1 (0.50) | — | |
| SCHEMBL444298 | 0.83 | ALDH1A1 (0.43) | — | |
| SCHEMBL269288 | 0.83 | — | — | |
| SCHEMBL8459302 | 0.81 | LMNA (0.46) | — | |
| SCHEMBL9262114 | 0.81 | LMNA (0.46) | — | |
| SCHEMBL7794503 | 0.80 | — | — | |
| SCHEMBL5274110 | 0.78 | LMNA (0.43) | — | |
| SCHEMBL9142070 | 0.77 | ALDH1A1 (0.36) | — | |
| SCHEMBL9263682 | 0.77 | LMNA (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352689-A | Rhizoxin derivatives and their use as anti-tumor agents | SANKYO COMPANY, LIMITED (JP) | 1994-10-04 | — | — | US | claimed |
| CN-112566675-A | Freshening compositions comprising controlled release modulators | 阿里莱森斯有限公司 | 2021-03-26 | — | — | CN | disclosed |
| WO-2020194531-A1 | AGENT FOR REDUCING BLOOD UREMIC SUBSTANCE | 国立大学法人東北大学 | 2020-10-01 | — | — | WO | disclosed |
| US-20170312200-A1 | AN AGENT FOR IMPROVING MITOCHONDRIAL FUNCTION | SHOWA DENKO K.K. (JP) | 2017-11-02 | — | — | US | disclosed |
| EP-3213739-A1 | AGENT FOR IMPROVING MITOCHONDRIAL FUNCTION AND ANTI-AGING COMPOSITION | Showa Denko K.K. (JP) | 2017-09-06 | — | — | EP | disclosed |
| US-20150329754-A1 | LIQUID COMPOSITION | DAICEL CORPORATION (JP) | 2015-11-19 | — | — | US | disclosed |
| US-7846970-B2 | Hydroxycitric acid derivatives and skin external preparations containing the same | SHOWA DENKO K.K. (JP) | 2010-12-07 | — | — | US | disclosed |
| US-20080234224-A1 | External Preparation For Skin | SHOWA DENKO K.K. (JP) | 2008-09-25 | — | — | US | disclosed |
| US-20070293577-A1 | Hydroxycitric Acid Derivatives And Skin External Preparations Using The Same | SHOWA DENKO K.K. (JP) | 2007-12-20 | — | — | US | disclosed |
| US-20070232698-A1 | Slimming Skin External Preparation and Cosmetic Containing the Same | SHOWA DENKO K.K. (JP) | 2007-10-04 | — | — | US | disclosed |
| US-20030157037-A1 | Use of aryl oximes for the prophylaxis and/or treatment of erythema formation and/or inflammatory reaction of the skin | MERCK PATENT GMBH (DE) | 2003-08-21 | — | — | US | disclosed |
| US-5391564-A | E.g., rhizoxin-13-yl 3-methylthiopropionate; anticarcinogenic agents | SANKYO COMPANY, LIMITED (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5389626-A | 3-aryloxmethyl-cephalosporin derivatives, and their medical use | SANKYO COMPANY, LIMITED (JP) | 1995-02-14 | — | — | US | disclosed |
| US-5352689-A | Rhizoxin derivatives and their use as anti-tumor agents | SANKYO COMPANY, LIMITED (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0350315-B1 | RHIZOXIN DERIVATES AND THEIR USE AS ANTI-TUMOR AGENTS | SANKYO COMPANY LIMITED (JP) | 1993-06-16 | — | — | EP | disclosed |
| EP-0363223-A2 | 3-Aryloxymethyl-cephalosporin derivatives, their preparation and their medical use | Sankyo Company Limited (JP) | 1990-04-11 | — | — | EP | disclosed |
| EP-0350315-A1 | Rhizoxin derivates and their use as anti-tumor agents | SANKYO COMPANY LIMITED (JP) | 1990-01-10 | — | — | EP | disclosed |
| US-4288454-A | Antiviral 1-adamantyl-3-(phenylsulfonyl)thioureas | HOFFMAN-LA ROCHE INC. (US) | 1981-09-08 | — | — | US | disclosed |
| US-4096145-A | DYES FOR RESINS AND POLYESTER TEXTILES | BASF AKTIENGESELLSCHAFT (DT) | 1978-06-20 | — | — | US | disclosed |
| US-3950321-A | POLYESTERS | BASF AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | disclosed |