SCHEMBL444298

SCHEMBL444298

CCCCCC(CC)C[C]=O

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
LMNA P02545 1/20 0.43
CYP3A4 P08684 3/20 0.41
TSHR P16473 2/20 0.41
CA2 P00918 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
GPR84 Q9NQS5 7/20 0.39
FFAR1 O14842 1/20 0.39
MAPT P10636 1/20 0.38
PRSS1 P07477 1/20 0.37
PRSS2 P07478 1/20 0.37
PRSS3 P35030 1/20 0.37
ATM Q13315 1/20 0.36
OPRM1 P35372 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9262114 0.98 LMNA (0.46) ALDH1A1TDP1LMNACYP3A4TSHR
SCHEMBL8459302 0.98 LMNA (0.46) ALDH1A1TDP1LMNACYP3A4TSHR
SCHEMBL78111 0.93 ALDH1A1 (0.50) ALDH1A1TDP1CYP3A4TSHRCA2
SCHEMBL9425652 0.91 LMNA (0.46) LMNAGPR84FFAR1MAPTOPRM1
SCHEMBL27538738 0.88 LMNA (0.50) LMNAGPR84FFAR1MAPT
SCHEMBL16196233 0.88 LMNA (0.50) LMNAGPR84FFAR1MAPT
SCHEMBL5274110 0.86 LMNA (0.43) LMNAGPR84FFAR1MAPTOPRM1
SCHEMBL8705110 0.84 LMNA (0.46) LMNAGPR84FFAR1MAPT
SCHEMBL9263682 0.84 LMNA (0.46) LMNAGPR84FFAR1MAPT
SCHEMBL2870649 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 430 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3109254-B1 CROSSLINKED NUCLEOSIDE AND NUCLEOTIDE UNIV OSAKA (JP) 2018-04-11 EP claimed
US-20140350269-A1 Acetals Esters Produced from Purified Glycerin for Use and Application as Emollients, Lubricants, Plasticizers, Solvents, Coalescents, Humectant, Polymerization Monomers, Additives to Biofuels GLYCEROSOLUTION QUÍMICA LTDA. (BR) 2014-11-27 US claimed
EP-2799433-A2 Acetals esters produced from purified glycerin for use and application as emollients, lubricants, plasticizers, solvents, coalescents, humectant, polymerization monomers, additives to biofuels Glycerosolution Quimica, Ltda (BR) 2014-11-05 EP claimed
WO-2024135721-A1 METHOD FOR PRODUCING PRODUCTION INTERMEDIATE, PRODUCTION INTERMEDIATE THEREOF, AND METHOD FOR PRODUCING CROSSLINKED ARTIFICIAL NUCLEIC ACID INTERMEDIATE BY USING SAME 田辺三菱製薬株式会社 2024-06-27 WO disclosed
WO-2024101446-A1 MODIFIED NUCLEOSIDE HAVING GUANIDINO STRUCTURE IN BRIDGED PART AND METHOD FOR PRODUCING OLIGONUCLEOTIDE USING SAME ルクサナバイオテク株式会社 2024-05-16 WO disclosed
CN-112513062-B Oligonucleotide-containing small cell lung cancer therapeutic agent 国立大学法人大阪大学 2024-05-10 CN disclosed
US-20240148775-A1 OLIGONUCLEOTIDE FOR INDUCING N-EXON SKIPPING DURING REST MRNA PRECURSOR PROCESSING OSAKA UNIVERSITY (JP) 2024-05-09 US disclosed
CN-117964674-A Bridged artificial nucleic acid ALNA 田边三菱制药株式会社 2024-05-03 CN disclosed
CN-117964673-A Bridged artificial nucleic acid ALNA 田边三菱制药株式会社 2024-05-03 CN disclosed
US-11939421-B2 Or relating to curing agents HEXCEL COMPOSITES LIMITED (GB) 2024-03-26 US disclosed
US-11879052-B2 Curatives HEXCEL COMPOSITES LIMITED (GB) 2024-01-23 US disclosed
CN-1157286-A N,N-dimethyl-1-t-butoxycarbonyl-4-phenylpiperidine-4-carboxamide SANKYO CO (JP) 1997-08-20 CN disclosed
EP-0776893-A1 Azaheterocyclic compounds having tachykinin receptor antagonist activity; Nk1 and NK2 SANKYO COMPANY LIMITED (JP) 1997-06-04 EP disclosed
US-5556864-A TREATMENT OF CIRCULATORY DISEASES AND PSYCHOSIS SANKYO COMPANY, LIMITED (JP) 1996-09-17 US disclosed
EP-0536936-B1 Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use SANKYO CO (JP) 1996-08-14 EP disclosed
EP-0600717-A1 Phenoxyalkylamines, -pyrrolidines and -piperidines for the treatment and prevention of circulatory diseases and psychosis SANKYO COMPANY LIMITED (JP) 1994-06-08 EP disclosed
EP-0583971-A1 Piperidine derivatives SANKYO COMPANY LIMITED (JP) 1994-02-23 EP disclosed
EP-0536936-A1 Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use Sankyo Company Limited (JP) 1993-04-14 EP disclosed
US-4379780-A 17 α-Dihydroequilin hapten and assay method AMERICAN HOME PRODUCTS CORPORATION (US) 1983-04-12 US disclosed
US-4379779-A Equilin hapten and assay method AMERICAN HOME PRODUCTS CORPORATION (US) 1983-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140350269-A1 Acetals Esters Produced from Purified Glycerin for Use and Application as Emollients, Lubricants, Plasticizers, Solvents, Coalescents, Humectant, Polymerization Monomers, Additives to Biofuels GK, DAGLA, DAGLB ALDH1A1 731/4885TDP1 452/4885LMNA 1568/4885
US-20240148775-A1 OLIGONUCLEOTIDE FOR INDUCING N-EXON SKIPPING DURING REST MRNA PRECURSOR PROCESSING UPF1, RBM17, NSUN2 ALDH1A1 3895/4885TDP1 328/4885LMNA 385/4885
US-11939421-B2 Or relating to curing agents FABP4, RARA, ADIPOR1 ALDH1A1 131/4885TDP1 1408/4885LMNA 585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.