Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262114 | 1.00 | LMNA (0.46) | LMNAGPR84FFAR1ALDH1A1TDP1 | |
| SCHEMBL444298 | 0.98 | ALDH1A1 (0.43) | LMNAGPR84FFAR1ALDH1A1TDP1 | |
| SCHEMBL78111 | 0.91 | ALDH1A1 (0.50) | ALDH1A1TDP1CYP3A4TSHRL3MBTL1 | |
| SCHEMBL27538738 | 0.91 | LMNA (0.50) | LMNAGPR84FFAR1MAPTFFAR4 | |
| SCHEMBL16196233 | 0.91 | LMNA (0.50) | LMNAGPR84FFAR1MAPTFFAR4 | |
| SCHEMBL9425652 | 0.89 | LMNA (0.46) | LMNAGPR84FFAR1MAPTFFAR4 | |
| SCHEMBL8705110 | 0.87 | LMNA (0.46) | LMNAGPR84FFAR1MAPTFFAR4 | |
| SCHEMBL9263682 | 0.87 | LMNA (0.46) | LMNAGPR84FFAR1MAPTFFAR4 | |
| SCHEMBL11797907 | 0.85 | ALDH1A1 (0.35) | LMNAALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL5274110 | 0.84 | LMNA (0.43) | LMNAGPR84FFAR1MAPTFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888992-A | PROTEASE INHIBITOR; VIRICIDE | NARHEX LIMITED (HK) | 1999-03-30 | — | — | US | disclosed |