Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 7/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 6/20 | 0.48 |
| ▸ | CDK2 | P24941 | 6/20 | 0.45 |
| ▸ | CDK1 | P06493 | 3/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28685100 | 0.81 | PDGFRB (0.44) | PARP10PARP15MAP4K4 | |
| SCHEMBL28707329 | 0.79 | PDGFRB (0.43) | PARP10MAP4K4 | |
| SCHEMBL30253716 | 0.76 | PARP10 (0.42) | PARP10MAP4K4 | |
| SCHEMBL28685072 | 0.76 | PARP10 (0.42) | PARP10MAP4K4 | |
| SCHEMBL30253497 | 0.76 | SIRT6 (0.33) | — | |
| SCHEMBL28698965 | 0.76 | SIRT6 (0.33) | — | |
| SCHEMBL28691237 | 0.75 | IKBKB (0.39) | — | |
| SCHEMBL28685074 | 0.75 | MAPT (0.39) | PARP10 | |
| SCHEMBL30253592 | 0.75 | IKBKB (0.39) | — | |
| SCHEMBL28644566 | 0.73 | SIRT6 (0.36) | ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113336713-A | Preparation method of alkoxy pyrazine derivative and alkoxy pyrazine derivative | 中国人民解放军军事科学院军事医学研究院 | 2021-09-03 | — | — | CN | claimed |
| CN-113336713-B | Preparation method of alkoxy pyrazine derivative and alkoxy pyrazine derivative | 中国人民解放军军事科学院军事医学研究院 | 2023-03-17 | — | — | CN | disclosed |
| CN-113336713-A | Preparation method of alkoxy pyrazine derivative and alkoxy pyrazine derivative | 中国人民解放军军事科学院军事医学研究院 | 2021-09-03 | — | — | CN | disclosed |