Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | LDHB | P07195 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8143170 | 0.69 | MAPT (0.43) | MAPTALDH1A1LMNAKDM4EGAA | |
| SCHEMBL21624879 | 0.68 | MAPT (0.55) | MAPTALDH1A1LMNAKDM4EGAA | |
| SCHEMBL29523988 | 0.67 | RAB9A (0.50) | MAPTALDH1A1LMNAKDM4EGAA | |
| SCHEMBL28714589 | 0.66 | RAB9A (0.49) | MAPTALDH1A1LMNAKDM4EGAA | |
| SCHEMBL3651005 | 0.66 | HDAC3 (0.59) | MAPTALDH1A1LMNAKDM4EGAA | |
| SCHEMBL14922314 | 0.66 | NPSR1 (0.63) | MAPTALDH1A1LMNAKDM4EGAA | |
| SCHEMBL5324137 | 0.65 | CYP2C9 (0.62) | MAPTALDH1A1LMNAKDM4EGAA | |
| SCHEMBL22891162 | 0.64 | CHRNB2 (0.38) | MAPTALDH1A1LMNAGAAKMT2A | |
| SCHEMBL22891175 | 0.64 | CHKA (0.38) | MAPTALDH1A1LMNAKDM4EGAA | |
| SCHEMBL22890978 | 0.64 | NPC1 (0.37) | MAPTALDH1A1LMNAKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114341141-A | Camptothecin derivatives having a disulfide moiety and a piperazine moiety | 太阳医药高级研究有限公司 | 2022-04-12 | — | — | CN | disclosed |