SCHEMBL21624879

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17316376	0.88	LIPE (0.51)	MAPTALDH1A1LMNAKDM4EGAA
	SCHEMBL11872337	0.87	MAPT (0.54)	MAPTALDH1A1LMNAKDM4EGAA
	SCHEMBL23387298	0.86	ALDH1A1 (0.52)	MAPTALDH1A1LMNAKDM4EGAA
	SCHEMBL6596281	0.85	LIPE (0.62)	MAPTALDH1A1LMNAKDM4EGAA
	SCHEMBL2370530	0.85	SMN1; SMN2 (0.60)	MAPTALDH1A1LMNAGAANPC1
	SCHEMBL24059107	0.84	LIPE (0.50)	MAPTALDH1A1LMNAKDM4EGAA
	SCHEMBL8349447	0.84	ADRB1 (0.50)	MAPTALDH1A1LMNAKDM4EGAA
	SCHEMBL11848012	0.84	LIPE (0.48)	MAPTALDH1A1LMNAKDM4EGAA
	SCHEMBL29098498	0.83	S1PR1 (0.60)	MAPTALDH1A1LMNAKDM4EGAA
	SCHEMBL17420453	0.83	AGXT (0.56)	MAPTALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.