Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28302432 | 0.71 | MEN1 (0.45) | MEN1KMT2AALDH1A1HSD17B10GABRA5 | |
| SCHEMBL5592616 | 0.69 | MEN1 (0.40) | MEN1KMT2AALDH1A1HSD17B10GABRA5 | |
| SCHEMBL28031249 | 0.69 | MEN1 (0.63) | MEN1KMT2AALDH1A1HSD17B10GABRA5 | |
| SCHEMBL28316724 | 0.68 | GABRA5 (0.32) | MEN1KMT2AALDH1A1HSD17B10GABRA5 | |
| SCHEMBL15581617 | 0.68 | MEN1 (0.41) | MEN1KMT2AALDH1A1HSD17B10GABRA5 | |
| SCHEMBL5544014 | 0.67 | SMN1; SMN2 (0.57) | ALDH1A1HSD17B10GABRA5GABRB2RAB9A | |
| SCHEMBL5600338 | 0.67 | MEN1 (0.37) | MEN1KMT2AALDH1A1HSD17B10GABRA5 | |
| SCHEMBL13412480 | 0.65 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1HSD17B10GABRA5 | |
| SCHEMBL1797901 | 0.65 | GABRA5 (0.72) | MEN1KMT2AALDH1A1HSD17B10GABRA5 | |
| SCHEMBL2895259 | 0.65 | GABRA5 (0.47) | MEN1KMT2AALDH1A1HSD17B10GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790164-B | Purine and 3-deazapurine analogues as choline kinase inhibitors | 内尔维亚诺医疗科学公司 | 2022-01-25 | — | — | CN | disclosed |