Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5600338 | 0.81 | MEN1 (0.37) | MEN1KMT2AALDH1A1HSD17B10GABRA5 | |
| SCHEMBL28366435 | 0.75 | GABRA5 (0.36) | MEN1KMT2AALDH1A1HSD17B10GABRA5 | |
| SCHEMBL28320024 | 0.73 | GABRA5 (0.35) | MEN1KMT2AALDH1A1HSD17B10GABRA5 | |
| SCHEMBL28316724 | 0.71 | GABRA5 (0.32) | MEN1KMT2AALDH1A1HSD17B10GABRA5 | |
| SCHEMBL28708312 | 0.69 | MEN1 (0.36) | MEN1KMT2AALDH1A1HSD17B10GABRA5 | |
| SCHEMBL28803151 | 0.69 | AOC3 (0.33) | HSD17B10GABRA5GABRB2HDAC4HDAC6 | |
| SCHEMBL15881332 | 0.68 | POLB (0.43) | KMT2AALDH1A1KDM4EHPGDGAA | |
| SCHEMBL28392788 | 0.68 | PARP1 (0.38) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL29000383 | 0.68 | AOC3 (0.39) | KMT2AALDH1A1HPGDNPC1SMN1; SMN2 | |
| SCHEMBL28366125 | 0.67 | KDM4E (0.31) | ALDH1A1HSD17B10GABRA5GABRB2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017728-A2 | NOVEL HETEROCYCLIC COMPOUNDS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-02-15 | — | — | WO | claimed |
| WO-2007017728-A2 | NOVEL HETEROCYCLIC COMPOUNDS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-02-15 | — | — | WO | disclosed |