Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 3/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2340169 | 0.72 | GAA (0.42) | DUTBACE1MAPT | |
| SCHEMBL23530049 | 0.71 | HCAR2 (0.33) | PREP | |
| SCHEMBL14745382 | 0.71 | NOS1 (0.34) | DUT | |
| SCHEMBL21062158 | 0.70 | DUT (0.30) | DUT | |
| SCHEMBL29997290 | 0.70 | DUT (0.30) | DUT | |
| SCHEMBL3408685 | 0.70 | IDO1 (0.53) | BACE1MAPT | |
| SCHEMBL28496615 | 0.70 | DUT (0.33) | DUTBACE1 | |
| SCHEMBL28529125 | 0.70 | USP2 (0.40) | DUTPREPBACE1 | |
| SCHEMBL481257 | 0.69 | IDO1 (0.50) | DUTMAPTHPGD | |
| SCHEMBL7426757 | 0.69 | HRH4 (0.46) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114008044-A | Pyridyl or pyrimidinyl MTOR kinase inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2022-02-01 | — | — | CN | disclosed |