Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 3/20 | 0.55 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.55 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GMNN | O75496 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2863429 | 1.00 | BLM (0.55) | BLMHSPD1HSPE1LMNAMEN1 | |
| SCHEMBL2864585 | 1.00 | BLM (0.55) | BLMHSPD1HSPE1LMNAMEN1 | |
| SCHEMBL2872960 | 1.00 | BLM (0.55) | BLMHSPD1HSPE1LMNAMEN1 | |
| SCHEMBL2869644 | 1.00 | BLM (0.55) | BLMHSPD1HSPE1LMNAMEN1 | |
| SCHEMBL2865743 | 1.00 | BLM (0.55) | BLMHSPD1HSPE1LMNAMEN1 | |
| SCHEMBL2870981 | 1.00 | BLM (0.55) | BLMHSPD1HSPE1LMNAMEN1 | |
| SCHEMBL2864433 | 0.90 | ALDH1A1 (0.53) | BLMHSPD1HSPE1LMNAMEN1 | |
| SCHEMBL2864717 | 0.88 | BLM (0.48) | BLMHSPD1HSPE1LMNAMEN1 | |
| SCHEMBL2872010 | 0.88 | BLM (0.48) | BLMHSPD1HSPE1LMNAMEN1 | |
| SCHEMBL2868494 | 0.88 | BLM (0.48) | BLMHSPD1HSPE1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023074894-A1 | CARTILAGE REGENERATION PROMOTER | 小林製薬株式会社 | 2023-05-04 | — | — | WO | disclosed |
| US-20170312200-A1 | AN AGENT FOR IMPROVING MITOCHONDRIAL FUNCTION | SHOWA DENKO K.K. (JP) | 2017-11-02 | — | — | US | disclosed |
| EP-3213739-A1 | AGENT FOR IMPROVING MITOCHONDRIAL FUNCTION AND ANTI-AGING COMPOSITION | Showa Denko K.K. (JP) | 2017-09-06 | — | — | EP | disclosed |
| EP-1799631-B1 | HYDROXYCITRIC ACID DERIVATIVES AND SKIN EXTERNAL PREPARATIONS CONTAINING THE SAME | SHOWA DENKO KK (JP) | 2017-01-25 | — | — | EP | disclosed |
| US-7846970-B2 | Hydroxycitric acid derivatives and skin external preparations containing the same | SHOWA DENKO K.K. (JP) | 2010-12-07 | — | — | US | disclosed |
| US-20070293577-A1 | Hydroxycitric Acid Derivatives And Skin External Preparations Using The Same | SHOWA DENKO K.K. (JP) | 2007-12-20 | — | — | US | disclosed |
| US-20070232698-A1 | Slimming Skin External Preparation and Cosmetic Containing the Same | SHOWA DENKO K.K. (JP) | 2007-10-04 | — | — | US | disclosed |
| EP-1811949-A1 | TOPICAL SLIMMING PREPARATION AND A COSMETIC CONTAINING A CARNITINE DERIVATIVE | SHOWA DENKO KABUSHIKI KAISHA (JP) | 2007-08-01 | — | — | EP | disclosed |
| EP-1799631-A1 | HYDROXYCITRIC ACID DERIVATIVES AND SKIN EXTERNAL PREPARATIONS CONTAINING THE SAME | Showa Denko K.K. (JP) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006033476-A1 | HYDROXYCITRIC ACID DERIVATIVES AND SKIN EXTERNAL PREPARATIONS CONTAINING THE SAME | SHOWA DENKO K.K. (JP) | 2006-03-30 | — | — | WO | disclosed |
| WO-2005115326-A1 | TOPICAL SLIMMING PREPARATION AND A COSMETIC CONTAINING A CARNITINE DERIVATIVE | SHOWA DENKO K.K. (JP) | 2005-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170312200-A1 | AN AGENT FOR IMPROVING MITOCHONDRIAL FUNCTION | UQCRC1, ACAD9, CYP27B1 | BLM 2978/4885HSPD1 75/4885HSPE1 54/4885 |
| US-20070293577-A1 | Hydroxycitric Acid Derivatives And Skin External Preparations Using The Same | HAAO, CYP8B1, CUTA | BLM 2887/4885HSPD1 271/4885HSPE1 80/4885 |
| US-20070232698-A1 | Slimming Skin External Preparation and Cosmetic Containing the Same | CPT1B, CUTA, LPL | BLM 3532/4885HSPD1 2328/4885HSPE1 2195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.