SCHEMBL2870993

SCHEMBL2870993

Cc1ccccc1-c1ccc(O)c(O)c1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.48
MCL1 Q07820 2/20 0.43
HPGD P15428 5/20 0.42
SMN1; SMN2 Q16637 5/20 0.42
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
MAPT P10636 5/20 0.42
ALOX15 P16050 4/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP3A4 P08684 2/20 0.42
KDM4E B2RXH2 1/20 0.42
BCL2 P10415 1/20 0.42
ALOX12 P18054 1/20 0.42
MAOA P21397 1/20 0.42
APEX1 P27695 1/20 0.42
MAPK1 P28482 1/20 0.42
RECQL P46063 1/20 0.42
DAPK1 P53355 1/20 0.42
CYP1B1 Q16678 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2860152 0.85 TRPA1 (0.46) TRPA1MCL1HPGDSMN1; SMN2MEN1
SCHEMBL30238150 0.84 TRPA1 (0.62) TRPA1MCL1HPGDSMN1; SMN2MEN1
SCHEMBL5587775 0.84 TRPA1 (0.62) TRPA1MCL1HPGDSMN1; SMN2MEN1
SCHEMBL18948647 0.84 HPGD (0.50) MCL1HPGDSMN1; SMN2MEN1KMT2A
SCHEMBL11253410 0.82 MCL1 (0.40) TRPA1MCL1HPGDSMN1; SMN2MEN1
SCHEMBL1005238 0.81 ALDH1A1 (0.57) TRPA1MCL1HPGDSMN1; SMN2KMT2A
SCHEMBL30343017 0.80 TRPA1 (0.42) TRPA1MCL1HPGDSMN1; SMN2MEN1
SCHEMBL673891 0.79 ALDH1A1 (0.62) TRPA1MCL1HPGDSMN1; SMN2KMT2A
SCHEMBL14417400 0.78 IDO1 (0.56) MCL1HPGDSMN1; SMN2MEN1KMT2A
SCHEMBL15512030 0.78 KDM4E (0.39) TRPA1MCL1HPGDSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365540-A1 SMALL MOLECULE INHIBITORS OF ENPP1 THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-11-16 US disclosed
CN-109983103-B Metal working oil composition and metal working method 出光兴产株式会社 2022-01-18 CN disclosed
US-20210139390-A1 PRODUCTION METHOD OF ORGANIC COMPOUND UNITIKA LTD. (JP) 2021-05-13 US disclosed
EP-3819283-A1 METHOD FOR PRODUCING ORGANIC COMPOUND Unitika Ltd. (JP) 2021-05-12 EP disclosed
WO-2020009016-A1 METHOD FOR PRODUCING ORGANIC COMPOUND ユニチカ株式会社 2020-01-09 WO disclosed
CN-102002139-A Method for preparing modified phenolic resin for coating with cresol residue LANZHOU PETROCHEMICAL COLLEGE OF VOCATIONAL TECHNOLOGY 2011-04-06 CN disclosed
CN-101967333-A Method for preparing phenolic resin from phenols residues and application thereof to production of coating LANZHOU PETROCHEMICAL VOC TECH COLLEGE 2011-02-09 CN disclosed
US-7713449-B2 Polymer electrolytic material, polymer electrolytic part, membrane electrode assembly, and polymer electrolyte fuel cell TORAY INDUSTRIES, INC. (JP) 2010-05-11 US disclosed
EP-1270646-B1 RESIN COMPOSITION AND ARTICLES MOLDED THEREFROM TORAY INDUSTRIES (JP) 2008-11-26 EP disclosed
US-7442757-B2 Resin, resin composition, method for manufacturing the same, and molded material including the same TORAY INDUSTRIES, INC. (JP) 2008-10-28 US disclosed
CN-100364160-C Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell TORAY INDUSTRIES (JP) 2008-01-23 CN disclosed
US-20060180796-A1 Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell TORAY INDUSTRIES, INC. (JP) 2006-08-17 US disclosed
US-20060047104-A1 Resin, resin composition, process for production thereof, and moldings made by using the same TORAY INDUSTRIES, INC. (JP) 2006-03-02 US disclosed
EP-1619735-A1 POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE PART, MEMBRANE ELECTRODE COMPOSITE AND POLYMER ELECTROLYTE TYPE FUEL CELL TORAY INDUSTRIES, INC. (JP) 2006-01-25 EP disclosed
EP-1518884-A1 RESIN, RESIN COMPOSITIONS, PROCESS FOR PRODUCTION THEREOF, AND MOLDINGS MADE BY USING THE SAME TORAY INDUSTRIES, INC. (JP) 2005-03-30 EP disclosed
US-6750313-B2 HIGH REFRACTIVE INDEX AND LOW DISPERSION CHARACTERISTICS; OPTICAL LENSES, FILMS, DISCS; POLYCARBONATE RESIN CONTAINING A PHOSPHONIC ACID GROUP TORAY INDUSTRIES, INC. (JP) 2004-06-15 US disclosed
US-20030013836-A1 Resin composition and articles molded therefrom TORAY INDUSTRIES, INC., A CORPORATION OF JAPAN (JP) 2003-01-16 US disclosed
EP-1270646-A1 RESIN COMPOSITION AND ARTICLES MOLDED THEREFROM TORAY INDUSTRIES, INC. (JP) 2003-01-02 EP disclosed
EP-0943640-A1 HIGHLY HEAT-RESISTANT, HIGH-PURITY POLYARYLATE AND FILM PRODUCED FROM THE SAME UNITIKA LTD. (JP) 1999-09-22 EP disclosed
US-5501936-A IMPROVED RESOLUTION OF VERY FINE PATTERNS TOKYO OHKA KOGYO CO., LTD. (JP) 1996-03-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230365540-A1 SMALL MOLECULE INHIBITORS OF ENPP1 ENPP1, ENPP2, ENPP3 TRPA1 4796/4885MCL1 2179/4885HPGD 1785/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.