Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.35 |
| ▸ | BBOX1 | O75936 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL2704201 | 0.87 | BBOX1 (0.52) | BBOX1LMNAABCC4MAPTKMT2A | |
| Bicarbonate SCHEMBL2704202 | 0.83 | BBOX1 (0.59) | BBOX1LMNAKMT2AATMBCHE | |
| Acrylic Acid SCHEMBL27587559 | 0.83 | LMNA (0.50) | BBOX1LMNAKMT2AATMBCHE | |
| SCHEMBL1016252 | 0.81 | BBOX1 (0.47) | BBOX1LMNAABCC4MAPTKMT2A | |
| Acrylic Acid SCHEMBL28444109 | 0.81 | LMNA (0.48) | BBOX1LMNAKMT2AATMBCHE | |
| Acrylic Acid SCHEMBL1356182 | 0.81 | LMNA (0.48) | BBOX1LMNAKMT2AATMBCHE | |
| Bicarbonate SCHEMBL2836768 | 0.81 | BBOX1 (0.57) | BBOX1KMT2AATMBCHEACHE | |
| Maleic Acid SCHEMBL9664934 | 0.81 | BBOX1 (0.47) | BBOX1LMNAEGLN1ABCC4MAPT | |
| Acrylic Acid SCHEMBL20983701 | 0.81 | LMNA (0.48) | BBOX1LMNAKMT2AATMBCHE | |
| Bicarbonate SCHEMBL5911592 | 0.81 | BBOX1 (0.57) | BBOX1KMT2AATMBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174379-A | Recovery and reuse of activators and initiators after polycarbonate synthesis | 阿卜杜拉国王科技大学 | 2022-03-11 | — | — | CN | disclosed |