Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | F11 | P03951 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | P4HB | P07237 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476747 | 0.83 | HIF1A (0.40) | DGAT1HIF1APRMT5WDR77GSK3A | |
| SCHEMBL28360858 | 0.79 | DGAT1 (0.35) | DGAT1HIF1AAAK1GSK3AGSK3B | |
| SCHEMBL16039956 | 0.77 | LIPG (0.48) | DGAT1AAK1LIPGF2F11 | |
| SCHEMBL28515790 | 0.77 | F2 (0.35) | DGAT1HIF1AAAK1PRMT5WDR77 | |
| SCHEMBL30404549 | 0.76 | LIPG (0.51) | DGAT1HIF1APRMT5WDR77GSK3A | |
| SCHEMBL15984293 | 0.75 | LIPG (0.39) | DGAT1HIF1AGSK3AGSK3BPDGFRB | |
| SCHEMBL2049952 | 0.75 | F11 (0.40) | DGAT1HIF1AGSK3AGSK3BPDGFRB | |
| SCHEMBL29633982 | 0.74 | PRMT5 (0.57) | DGAT1HIF1AAAK1PRMT5WDR77 | |
| SCHEMBL17966689 | 0.74 | PRMT5 (0.57) | DGAT1HIF1AAAK1PRMT5WDR77 | |
| SCHEMBL31227320 | 0.73 | LPL (0.44) | HIF1AGSK3AGSK3BLIPGF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563094-B | (hetero) aryl-substituted piperidinyl derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-03-18 | — | — | CN | disclosed |