Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21241302 | 0.80 | — | — | |
| SCHEMBL4573872 | 0.69 | SLC6A4 (0.37) | — | |
| SCHEMBL5078808 | 0.67 | NOTUM (0.31) | TSHR | |
| SCHEMBL5658620 | 0.65 | ALDH1A1 (0.37) | MEN1ALOX15TSHRMAPK1KMT2A | |
| SCHEMBL23159409 | 0.62 | — | — | |
| SCHEMBL4573868 | 0.61 | — | — | |
| SCHEMBL22893863 | 0.61 | LOXL2 (0.33) | — | |
| SCHEMBL28713544 | 0.61 | AR (0.35) | KIF11 | |
| SCHEMBL939256 | 0.60 | XDH (0.39) | ALOX15KMT2AHSD17B10 | |
| SCHEMBL880789 | 0.59 | ALDH1A1 (0.59) | MEN1TSHRMAPK1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206870-A | Tricyclic AKR1C3 dependent KARS inhibitors | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |