Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18343680 | 0.90 | SMN1; SMN2 (0.51) | SMN1; SMN2SYKLMNAAKT1CTSK | |
| SCHEMBL4152470 | 0.83 | SMN1; SMN2 (0.56) | SMN1; SMN2SYKLMNAAKT1CTSK | |
| SCHEMBL25002520 | 0.81 | SYK (0.53) | SMN1; SMN2SYKLMNAAKT1CTSK | |
| SCHEMBL3722611 | 0.78 | SYK (0.50) | SMN1; SMN2SYKLMNAAKT1 | |
| SCHEMBL29838906 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNACTSKATMCTSS | |
| SCHEMBL13269432 | 0.77 | SMN1; SMN2 (0.56) | SMN1; SMN2SYKLMNAAKT1CA12 | |
| SCHEMBL6352709 | 0.77 | AKT1 (0.48) | SMN1; SMN2SYKLMNAAKT1CTSK | |
| SCHEMBL4148951 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2SYKLMNAAKT1CTSK | |
| SCHEMBL4679985 | 0.76 | SYK (0.47) | SMN1; SMN2SYKCTSKBACE1 | |
| SCHEMBL421286 | 0.76 | SYK (0.61) | SMN1; SMN2SYKLMNAAKT1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3932909-B1 | BENZOINDAZOLONE COMPOUND, AND INTERMEDIATE THEREOF | LMITO THERAPEUTICS INC (KR) | 2025-04-02 | — | — | EP | disclosed |
| US-12187683-B2 | Benzoindazolone compound and intermediate thereof | LMITO THERAPEUTICS INC. (KR) | 2025-01-07 | — | — | US | disclosed |
| CN-113454068-B | Benzonazolone compounds and intermediates thereof | LMITO药业株式会社 | 2024-08-02 | — | — | CN | disclosed |
| US-20220144780-A1 | BENZOINDAZOLONE COMPOUND AND INTERMEDIATE THEREOF | LMITO THERAPEUTICS INC. (KR) | 2022-05-12 | — | — | US | disclosed |
| CN-113454068-A | Benzoindazolone compounds and intermediates thereof | LMITO药业株式会社 | 2021-09-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12187683-B2 | Benzoindazolone compound and intermediate thereof | NQO1, KEAP1, SQOR | SMN1; SMN2 2597/4885SYK 2078/4885LMNA 1476/4885 |
| US-20220144780-A1 | BENZOINDAZOLONE COMPOUND AND INTERMEDIATE THEREOF | NQO1, KEAP1, SQOR | SMN1; SMN2 2597/4885SYK 2078/4885LMNA 1476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.