Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18343680 | 0.89 | SMN1; SMN2 (0.51) | SMN1; SMN2ATMALDH1A1GAACTSK | |
| SCHEMBL7357959 | 0.82 | CTRB1 (0.52) | SMN1; SMN2ALDH1A1CTSKLMNACTSL | |
| SCHEMBL14291825 | 0.80 | ABCB1 (0.46) | SMN1; SMN2ATMALDH1A1NPC1RAB9A | |
| SCHEMBL8043863 | 0.79 | ALDH1A1 (0.53) | SMN1; SMN2ATMALDH1A1NPC1RAB9A | |
| SCHEMBL14321670 | 0.78 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1NPC1RAB9ACTSK | |
| SCHEMBL14321671 | 0.78 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1NPC1RAB9ACTSK | |
| SCHEMBL381080 | 0.78 | ABCB1 (0.53) | ALDH1A1CTSKLMNACTSLCTSB | |
| SCHEMBL7404261 | 0.78 | ABCB1 (0.53) | ALDH1A1CTSKLMNACTSLCTSB | |
| SCHEMBL381082 | 0.78 | ABCB1 (0.53) | ALDH1A1CTSKLMNACTSLCTSB | |
| SCHEMBL11868898 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1GAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022191338-A1 | LEVODOPA-PRODRUGS AND CARBIDOPA-PRODRUGS FOR USE IN THE TREATMENT OF PARKINSON'S DISEASE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2022-09-15 | — | — | WO | disclosed |