Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.76 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.46 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.39 |
| ▸ | CPN1 | P15169 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3517283 | 0.89 | FOLH1 (0.72) | FOLH1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL2872014 | 0.88 | — | — | |
| SCHEMBL3515562 | 0.87 | FOLH1 (0.73) | FOLH1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL2058227 | 0.87 | FOLH1 (1.00) | FOLH1ENPEPANPEP | |
| SCHEMBL19692362 | 0.87 | FOLH1 (0.61) | FOLH1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL16061483 | 0.87 | CHRM1 (0.76) | FOLH1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL16062298 | 0.87 | CHRM1 (0.76) | FOLH1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL2871927 | 0.87 | CHRM1 (0.76) | FOLH1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL28475733 | 0.86 | FOLH1 (0.62) | FOLH1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL3517925 | 0.85 | FOLH1 (0.74) | FOLH1CHRM1AKR1A1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1570835-B1 | Composition for the permanent deformation of the hair comprising at least one carboxydithiol | OREAL (FR) | 2010-10-20 | — | — | EP | claimed |
| US-20050208007-A1 | Composition to permanently reshape the hair containing at least one carboxydithiol | L'OREAL S.A. (FR) | 2005-09-22 | — | — | US | claimed |
| EP-1570835-A1 | Composition for the permanent deformatioh of the hair comprising at least one carboxydithiol | L'OREAL (FR) | 2005-09-07 | — | — | EP | claimed |
| US-20100190902-A1 | ALKYLTIN SULFANYL ESTER THIOLS | CHEMTURA CORPORATION (US) | 2010-07-29 | — | — | US | disclosed |
| US-20050208007-A1 | Composition to permanently reshape the hair containing at least one carboxydithiol | L'OREAL S.A. (FR) | 2005-09-22 | — | — | US | disclosed |
| EP-1570835-A1 | Composition for the permanent deformatioh of the hair comprising at least one carboxydithiol | L'OREAL (FR) | 2005-09-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190902-A1 | ALKYLTIN SULFANYL ESTER THIOLS | SULT1E1, SULT1A1, TST | FOLH1 4882/4885CHRM1 2348/4885AKR1A1 1093/4885 |
| US-20050208007-A1 | Composition to permanently reshape the hair containing at least one carboxydithiol | CTH, BHMT2, CRAT | FOLH1 68/4885CHRM1 3234/4885AKR1A1 1059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.