Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28720240 | 1.00 | RAB9A (0.42) | RAB9AHTR1AGAARXFP1MEN1 | |
| SCHEMBL29486879 | 1.00 | RAB9A (0.42) | RAB9AHTR1AGAARXFP1MEN1 | |
| SCHEMBL28703606 | 0.84 | CASP3 (0.42) | RAB9AMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL22918281 | 0.84 | CASP3 (0.42) | RAB9AMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL29486855 | 0.84 | CASP3 (0.42) | RAB9AMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL28713856 | 0.81 | PKM (0.39) | RAB9AMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL22918300 | 0.81 | PKM (0.39) | RAB9AMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL29486871 | 0.81 | PKM (0.39) | RAB9AMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL22918403 | 0.79 | HTR1A (0.43) | RAB9AHTR1AGAAMEN1ALDH1A1 | |
| SCHEMBL29852306 | 0.77 | CASP3 (0.35) | RAB9AGAAMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114286816-A | Difluoro-halogenated allylamine sulfone derivative inhibitor of lysyl oxidase, preparation method and application thereof | 法玛西斯有限公司 | 2022-04-05 | — | — | CN | disclosed |