SCHEMBL28720281

SCHEMBL28720281

NC1(N)CCC(CCc2ccccc2)(CCc2ccccc2)CC1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 6/20 0.47
MAOA P21397 4/20 0.47
MAOB P27338 4/20 0.47
CYP2A6 P11509 1/20 0.41
HTR2A P28223 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
RCOR1 Q9UKL0 4/20 0.41
ALDH1A1 P00352 1/20 0.40
OPRM1 P35372 2/20 0.39
GAA P10253 1/20 0.39
OPRD1 P41143 1/20 0.39
OPRL1 P41146 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5694869 0.82 HTR2A (0.48) KDM1AMAOAMAOBCYP2A6HTR2A
SCHEMBL29369076 0.79 MAOA (0.59) KDM1AMAOAMAOBLOXL2RCOR1
SCHEMBL5320724 0.78 ALDH1A1 (0.50) KDM1AMAOAMAOBCYP2A6HTR2A
SCHEMBL22444200 0.75 MAOA (0.48) KDM1AMAOAMAOBCYP2A6HTR2A
SCHEMBL21058245 0.73 MAOA (0.52) KDM1AMAOAMAOBCYP2A6HTR2A
SCHEMBL25401977 0.73 DPP4 (0.44) KDM1AMAOAMAOBCYP2A6HTR2A
SCHEMBL2437772 0.73 ALDH1A1 (0.38) KDM1AMAOAMAOBALDH1A1OPRM1
SCHEMBL21058274 0.72 MAOA (0.50) KDM1AMAOAMAOBCYP2A6HTR2A
SCHEMBL1824162 0.72 MAOA (0.50) KDM1AMAOAMAOBCYP2A6HTR2A
SCHEMBL20104705 0.72 MAOA (0.50) KDM1AMAOAMAOBCYP2A6HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114163334-B Modified alicyclic amine curing agent and preparation method thereof 万华化学集团股份有限公司 2023-07-14 CN disclosed
CN-114163334-A Modified alicyclic amine curing agent and preparation method thereof 万华化学集团股份有限公司 2022-03-11 CN disclosed