Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2444011 | 0.93 | CRHBP (0.39) | ALDH1A1NPC1OPRM1KDM1AMAOA | |
| SCHEMBL5320724 | 0.75 | ALDH1A1 (0.50) | ALDH1A1NPC1OPRM1KDM1AMAOA | |
| SCHEMBL5694869 | 0.75 | HTR2A (0.48) | ALDH1A1OPRM1KDM1AMAOAMAOB | |
| SCHEMBL28720281 | 0.73 | KDM1A (0.47) | ALDH1A1OPRM1KDM1AMAOAMAOB | |
| SCHEMBL2439643 | 0.69 | ALDH1A1 (0.41) | ALDH1A1NPC1OPRM1KDM1AMAOA | |
| SCHEMBL8348436 | 0.69 | MAOA (0.38) | ALDH1A1OPRM1MAOAMAOBGAA | |
| SCHEMBL4904161 | 0.68 | ALDH1A1 (0.56) | ALDH1A1NPC1OPRM1GAAOPRD1 | |
| SCHEMBL4901657 | 0.68 | ALDH1A1 (0.56) | ALDH1A1NPC1OPRM1GAAOPRD1 | |
| SCHEMBL25401977 | 0.67 | DPP4 (0.44) | ALDH1A1KDM1AMAOAMAOBSIGMAR1 | |
| SCHEMBL18092829 | 0.67 | ALDH1A1 (0.41) | ALDH1A1OPRM1KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2362765-A2 | PERFUME SYSTEMS | The Procter & Gamble Company (US) | 2011-09-07 | — | — | EP | claimed |
| WO-2010065446-A2 | PERFUME SYSTEMS | THE PROCTER & GAMBLE COMPANY (US) | 2010-06-10 | — | — | WO | claimed |