SCHEMBL28720334

SCHEMBL28720334

[CH2]Cc1cc(F)c(CO)c(F)c1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL523766 0.82 ACHE (0.43) TAAR1
SCHEMBL28713398 0.76
SCHEMBL12763658 0.76 TRPA1 (0.33) TAAR1
SCHEMBL10981699 0.76 TNKS (0.40)
SCHEMBL96131 0.74 CES2 (0.37) TAAR1
SCHEMBL147659 0.74 CES2 (0.36)
SCHEMBL22437204 0.73 ACVRL1 (0.40) TAAR1
SCHEMBL4048403 0.72 TAAR1 (0.58) TAAR1
SCHEMBL22437365 0.71 GCGR (0.36) TAAR1
SCHEMBL28116263 0.71 ACHE (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114174297-B Estrogen receptor modulating compounds 雷迪厄斯制药公司 2024-07-12 CN disclosed
CN-114174297-A Estrogen receptor modulating compounds 雷迪厄斯制药公司 2022-03-11 CN disclosed