SCHEMBL2872051

SCHEMBL2872051

CC(C)(C)c1ccc(C(c2ccc(C(C)(C)C)cc2)c2cccc3c2Cc2ccccc2-3)cc1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
ALDH1A1 P00352 1/20 0.34
PLA2G1B P04054 1/20 0.34
NFKB1 P19838 1/20 0.34
CASP3 P42574 1/20 0.34
NFKB2 Q00653 1/20 0.34
RELA Q04206 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ATG4B Q9Y4P1 1/20 0.34
PGR P06401 1/20 0.34
HTR7 P34969 1/20 0.33
HTR2B P41595 1/20 0.33
CYP17A1 P05093 1/20 0.31
EGFR P00533 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3157875 0.84 PNMT (0.41) PNMTNPC1RAB9AALDH1A1NFKB1
SCHEMBL3157927 0.83 PNMT (0.46) PNMTNPC1RAB9AALDH1A1PGR
SCHEMBL3157078 0.81 PNMT (0.41) PNMTNPC1RAB9AALDH1A1L3MBTL1
Tetrahydrofuran SCHEMBL8625099 0.75 PNMT (0.40) PNMTNPC1RAB9APGRHTR7
SCHEMBL3150001 0.75 IDO1 (0.40) PNMTALDH1A1HTR7
SCHEMBL6672847 0.73 PNMT (0.49) PNMTNPC1RAB9AALDH1A1PGR
SCHEMBL6675580 0.73 PNMT (0.49) PNMTNPC1RAB9AALDH1A1PGR
SCHEMBL29617348 0.73 PNMT (0.49) PNMTNPC1RAB9AALDH1A1PGR
SCHEMBL2873173 0.72 NPC1 (0.39) NPC1RAB9AALDH1A1PLA2G1BNFKB1
SCHEMBL6557930 0.72 PNMT (0.47) PNMTNPC1RAB9AALDH1A1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7767313-B2 Polypropylene composite film comprising a metallocene-catalyzed propylene/1-butene random copolymer MITSUI CHEMICALS, INC. (JP) 2010-08-03 US disclosed
US-7737239-B2 Propylene copolymer, polypropylene composition and uses thereof, transition metal compound and olefin polymerization catalyst MITSUI CHEMICALS, INC. (JP) 2010-06-15 US disclosed
US-7678934-B2 Propylene copolymer, polypropylene composition and uses thereof, transition metal compound and olefin polymerization catalyst MITSUI CHEMICALS, INC. (JP) 2010-03-16 US disclosed
EP-1985637-B1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization MITSUI CHEMICALS INC (JP) 2010-03-03 EP disclosed
EP-1985638-B1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization MITSUI CHEMICALS INC (JP) 2010-02-17 EP disclosed
EP-1614699-B9 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION MITSUI CHEMICALS INC (JP) 2009-12-16 EP disclosed
US-20080312461-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2008-12-18 US disclosed
US-20080306234-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2008-12-11 US disclosed
US-20080306219-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2008-12-11 US disclosed
US-20080292896-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2008-11-27 US disclosed
EP-1988104-A1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization Mitsui Chemicals, Inc. (JP) 2008-11-05 EP disclosed
EP-1985637-A1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization Mitsui Chemicals, Inc. (JP) 2008-10-29 EP disclosed
EP-1985638-A1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization Mitsui Chemicals, Inc. (JP) 2008-10-29 EP disclosed
EP-1614699-B1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION MITSUI CHEMICALS INC (JP) 2008-10-15 EP disclosed
US-20060276607-A1 Propylene copolymer, polypropylene composition, and uses thereof, transition metal compounds and catalyst for olefin polymerization MITSUI CHEMICALS, INC. (JP) 2006-12-07 US disclosed
EP-1614699-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION Mitsui Chemicals, Inc. (JP) 2006-01-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080312461-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST PPIA, PPOX, PTGES2 PNMT 438/4885NPC1 3727/4885RAB9A 4320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.