Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.48 |
| ▸ | NPC1 | O15118 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29654064 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9AKDM4EGAA | |
| SCHEMBL28701610 | 0.91 | ACHE (0.57) | SMN1; SMN2NPC1RAB9AKDM4EGAA | |
| SCHEMBL28720669 | 0.88 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AKDM4EGAA | |
| SCHEMBL29654116 | 0.87 | ACHE (0.56) | SMN1; SMN2NPC1RAB9AKDM4EGAA | |
| SCHEMBL28707179 | 0.87 | ACHE (0.56) | SMN1; SMN2NPC1RAB9AKDM4EGAA | |
| SCHEMBL28701609 | 0.78 | MAPT (0.53) | SMN1; SMN2NPC1RAB9AKDM4EGAA | |
| SCHEMBL28707178 | 0.74 | MAPT (0.57) | SMN1; SMN2NPC1RAB9AKDM4EGAA | |
| SCHEMBL5605821 | 0.72 | PI4K2A (0.57) | SMN1; SMN2NPC1RAB9AKDM4EGAA | |
| SCHEMBL397621 | 0.71 | ALDH1A1 (0.58) | SMN1; SMN2NPC1RAB9AKDM4EGAA | |
| SCHEMBL14384821 | 0.70 | POLB (0.59) | SMN1; SMN2NPC1RAB9AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114249702-B | N-aryl- [2,4 '-dithiazole ] -2' -amine compound and preparation and application thereof | 沈阳药科大学 | 2023-09-05 | — | — | CN | disclosed |
| CN-114249702-A | N-aryl- [2,4 '-bithiazole ] -2' -amine compound and preparation and application thereof | 沈阳药科大学 | 2022-03-29 | — | — | CN | disclosed |