Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17202712 | 1.00 | GNAI3 (0.42) | GNAI3GNAO1GNAI1FAAHMGLL | |
| SCHEMBL6566845 | 0.92 | POLB (0.38) | GNAI3GNAO1GNAI1FAAHMGLL | |
| SCHEMBL27903571 | 0.76 | MGLL (0.57) | GNAI3GNAO1GNAI1FAAHMGLL | |
| SCHEMBL27921301 | 0.76 | MGLL (0.57) | GNAI3GNAO1GNAI1FAAHMGLL | |
| SCHEMBL20360089 | 0.76 | MGLL (0.57) | GNAI3GNAO1GNAI1FAAHMGLL | |
| SCHEMBL28035741 | 0.76 | MGLL (0.57) | GNAI3GNAO1GNAI1FAAHMGLL | |
| Hydrochloric Acid SCHEMBL3402334 | 0.74 | MGLL (0.55) | GNAI3GNAO1GNAI1FAAHMGLL | |
| SCHEMBL8915607 | 0.74 | GNAI3 (0.41) | GNAI3GNAO1GNAI1FAAHMGLL | |
| SCHEMBL11209111 | 0.74 | ALOX5 (0.41) | GNAI3GNAO1GNAI1FAAHMGLL | |
| SCHEMBL22574843 | 0.73 | KDM4E (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111349155-B | Glucagon analogue and preparation method and application thereof | 浙江和泽医药科技股份有限公司 | 2022-04-05 | — | — | CN | disclosed |
| CN-111349155-A | Glucagon analogue and preparation method and application thereof | 杭州和泽医药科技有限公司 | 2020-06-30 | — | — | CN | disclosed |