Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 4/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | GALR3 | O60755 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28731543 | 1.00 | ALDH1A1 (0.36) | ALDH1A1KDM4EMAPTMAOAHCAR3 | |
| SCHEMBL28731906 | 0.84 | ALDH1A1 (0.35) | ALDH1A1KDM4EMAPTMAOAHCAR3 | |
| SCHEMBL28731907 | 0.84 | ALDH1A1 (0.35) | ALDH1A1KDM4EMAPTMAOAHCAR3 | |
| SCHEMBL22836000 | 0.84 | MAOA (0.36) | ALDH1A1KDM4EMAOA | |
| SCHEMBL26353445 | 0.84 | MAOA (0.36) | ALDH1A1KDM4EMAOA | |
| SCHEMBL29653373 | 0.84 | MAOA (0.36) | ALDH1A1KDM4EMAOA | |
| SCHEMBL28731548 | 0.83 | ITGB3 (0.34) | — | |
| SCHEMBL28731550 | 0.83 | ITGB3 (0.34) | — | |
| SCHEMBL22835245 | 0.83 | SCN1A (0.38) | ALDH1A1MAOA | |
| SCHEMBL26353444 | 0.83 | SCN1A (0.38) | ALDH1A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114437035-A | Compound for inhibiting and degrading IRAK4, pharmaceutical composition and pharmaceutical application thereof | 海思科医药集团股份有限公司 | 2022-05-06 | — | — | CN | disclosed |