Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28731550 | 1.00 | ITGB3 (0.34) | ITGB3ITGA2BSMN1; SMN2JAK2JAK1 | |
| SCHEMBL28731564 | 0.83 | GPR119 (0.37) | SMN1; SMN2 | |
| SCHEMBL28731544 | 0.83 | ALDH1A1 (0.36) | — | |
| SCHEMBL28731543 | 0.83 | ALDH1A1 (0.36) | — | |
| SCHEMBL28731906 | 0.76 | ALDH1A1 (0.35) | — | |
| SCHEMBL28731907 | 0.76 | ALDH1A1 (0.35) | — | |
| SCHEMBL29653373 | 0.68 | MAOA (0.36) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL26353445 | 0.68 | MAOA (0.36) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL22836000 | 0.68 | MAOA (0.36) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL22835245 | 0.68 | SCN1A (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114437035-A | Compound for inhibiting and degrading IRAK4, pharmaceutical composition and pharmaceutical application thereof | 海思科医药集团股份有限公司 | 2022-05-06 | — | — | CN | disclosed |