Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28731550 | 0.83 | ITGB3 (0.34) | SMN1; SMN2 | |
| SCHEMBL28731548 | 0.83 | ITGB3 (0.34) | SMN1; SMN2 | |
| SCHEMBL24779343 | 0.78 | TP53 (0.42) | GPR119TP53 | |
| SCHEMBL30291118 | 0.78 | TP53 (0.42) | GPR119TP53 | |
| SCHEMBL28731543 | 0.77 | ALDH1A1 (0.36) | — | |
| SCHEMBL28731544 | 0.77 | ALDH1A1 (0.36) | — | |
| SCHEMBL24779311 | 0.77 | TP53 (0.43) | GPR119TP53NR1D1 | |
| SCHEMBL24779105 | 0.76 | TP53 (0.41) | GPR119TP53 | |
| SCHEMBL30291011 | 0.76 | TP53 (0.41) | GPR119TP53 | |
| SCHEMBL1806667 | 0.75 | TP53 (0.43) | GPR119TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114437035-A | Compound for inhibiting and degrading IRAK4, pharmaceutical composition and pharmaceutical application thereof | 海思科医药集团股份有限公司 | 2022-05-06 | — | — | CN | disclosed |