Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | SIRT7 | Q9NRC8 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | VCP | P55072 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925617 | 0.79 | VCP (0.46) | TRPV1KDRFLT1FLT4VCP | |
| SCHEMBL29621008 | 0.77 | TRPV1 (0.56) | TRPV1KDRHDAC6 | |
| SCHEMBL22925839 | 0.76 | KMT2A (0.52) | TRPV1KDRFLT1FLT4KIF11 | |
| SCHEMBL22925576 | 0.75 | TRPV1 (0.47) | TRPV1KDRFLT1FLT4VCP | |
| SCHEMBL5319106 | 0.75 | SIRT7 (0.64) | TRPV1PIK3CAPIK3CGKDRFLT1 | |
| SCHEMBL31013395 | 0.74 | TRPV1 (0.58) | TRPV1KDRFLT1FLT4HDAC6 | |
| SCHEMBL22925571 | 0.74 | TRPV1 (0.49) | TRPV1KDRFLT1FLT4VCP | |
| SCHEMBL14057525 | 0.74 | TRPV1 (0.66) | TRPV1KDRFLT1FLT4SIRT7 | |
| SCHEMBL22925621 | 0.74 | ALOX5 (0.51) | TRPV1KDRFLT1FLT4VCP | |
| SCHEMBL22925652 | 0.74 | TRPV1 (0.50) | TRPV1KDRFLT1FLT4SIRT7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |