Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 3/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28060232 | 1.00 | CHRM1 (0.45) | CHRM1CHRM4CHRM5HRH3MMP8 | |
| SCHEMBL4750370 | 1.00 | CHRM1 (0.45) | CHRM1CHRM4CHRM5HRH3MMP8 | |
| SCHEMBL28042762 | 0.85 | HSD11B1 (0.42) | HRH3HSP90AA1KMT2AALDH1A1LMNA | |
| SCHEMBL6174347 | 0.82 | CYP2B6 (0.47) | LMNA | |
| SCHEMBL4750325 | 0.76 | HRH3 (0.39) | CHRM1CHRM4CHRM5HRH3ALDH1A1 | |
| SCHEMBL4976767 | 0.75 | HSD17B10 (0.46) | CHRM1KMT2AALDH1A1LMNAHSD11B1 | |
| SCHEMBL19000972 | 0.70 | HSD11B1 (0.65) | KMT2AALDH1A1LMNAHSD11B1MEN1 | |
| SCHEMBL2850013 | 0.69 | ALDH1A1 (0.70) | KMT2AALDH1A1LMNAMEN1TSHR | |
| SCHEMBL955395 | 0.69 | SMN1; SMN2 (0.40) | CHRM1CHRM4CHRM5HRH3KMT2A | |
| SCHEMBL5267307 | 0.69 | HSD11B1 (0.70) | KMT2AALDH1A1LMNAHSD11B1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109952301-B | 5-HT2C receptor agonists and compositions and methods of use | 艾尼纳制药公司 | 2022-03-25 | — | — | CN | disclosed |