Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28060232 | 0.76 | CHRM1 (0.45) | HRH3CHRM1CHRM4CHRM5ALDH1A1 | |
| SCHEMBL28737795 | 0.76 | CHRM1 (0.45) | HRH3CHRM1CHRM4CHRM5ALDH1A1 | |
| SCHEMBL4750370 | 0.76 | CHRM1 (0.45) | HRH3CHRM1CHRM4CHRM5ALDH1A1 | |
| SCHEMBL5235142 | 0.69 | CTSL (0.55) | ALDH1A1CYP2C19 | |
| SCHEMBL28042762 | 0.68 | HSD11B1 (0.42) | HRH3KCNH2ALDH1A1L3MBTL1 | |
| SCHEMBL4976767 | 0.67 | HSD17B10 (0.46) | CHRM1ALDH1A1 | |
| SCHEMBL8670678 | 0.66 | MAOA (0.55) | MAOB | |
| SCHEMBL3952085 | 0.66 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1 | |
| SCHEMBL2636547 | 0.66 | MEN1 (0.68) | HRH3KCNH2ALDH1A1L3MBTL1CYP2C9 | |
| SCHEMBL19182795 | 0.65 | CHRM3 (0.40) | CHRM1CHRM3KCNH2HRH1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |