SCHEMBL28738017

SCHEMBL28738017

C#CCOc1ccc2[nH]cc(O)c2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 3/20 0.41
MTNR1B P49286 2/20 0.41
EGFR P00533 1/20 0.41
IGF1R P08069 1/20 0.41
FLT4 P35916 1/20 0.41
KDR P35968 1/20 0.41
HTR1A P08908 5/20 0.41
HTR1B P28222 5/20 0.41
HTR1D P28221 4/20 0.41
CA12 O43570 3/20 0.40
CA4 P22748 3/20 0.40
CA9 Q16790 3/20 0.40
CA1 P00915 2/20 0.40
GSTP1 P09211 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
GPR84 Q9NQS5 1/20 0.39
HTT P42858 1/20 0.39
CYP2D6 P10635 1/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25057108 0.77 HTR1A (0.72) HTR1AHTR1BHTR1DCYP2D6KDM4E
SCHEMBL28506218 0.75 TRPM8 (0.64) HTR1AHTR1BHTR1DKDM4EALDH1A1
SCHEMBL21623872 0.74 GPR84 (0.62) MTNR1AMTNR1BHTR1AHTR1BHTR1D
SCHEMBL21292956 0.73 KMT2A (0.69) MTNR1AMTNR1BHTR1AHTR1BKDM4E
SCHEMBL19666080 0.73 KMT2A (0.69) MTNR1AMTNR1BHTR1AHTR1BKDM4E
SCHEMBL19666078 0.73 KMT2A (0.69) MTNR1AMTNR1BHTR1AHTR1BKDM4E
SCHEMBL25057107 0.73 HTR1D (0.55) MTNR1AMTNR1BHTR1AHTR1BHTR1D
Hydrochloric Acid SCHEMBL21292898 0.73 KMT2A (0.68) MTNR1AMTNR1BHTR1AHTR1BKDM4E
Hydrochloric Acid SCHEMBL21292896 0.73 KMT2A (0.68) MTNR1AMTNR1BHTR1AHTR1BKDM4E
SCHEMBL28511262 0.71 KMT2A (0.54) MTNR1AMTNR1BHTR1AHTR1BCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114502171-A Crosslinking compounds and methods of use thereof 北卡罗莱纳州立大学 2022-05-13 CN disclosed