Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 3/20 | 0.61 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | APP | P05067 | 2/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.57 |
| ▸ | TYR | P14679 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | IGF1R | P08069 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | BLM | P54132 | 3/20 | 0.55 |
| ▸ | APEX1 | P27695 | 2/20 | 0.55 |
| ▸ | THPO | P40225 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.55 |
| ▸ | RGS12 | O14924 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dihydrocaffeic Acid SCHEMBL245530 | 0.84 | IAPP (0.65) | IAPPLCKAPPCYP19A1TYR | |
| Dihydrocaffeic Acid SCHEMBL7058919 | 0.84 | IAPP (0.65) | IAPPLCKAPPCYP19A1TYR | |
| Dihydrocaffeic Acid SCHEMBL29351390 | 0.84 | IAPP (0.65) | IAPPLCKAPPCYP19A1TYR | |
| SCHEMBL28165571 | 0.82 | IAPP (0.82) | IAPPLCKAPPCYP19A1TYR | |
| SCHEMBL3383712 | 0.81 | IAPP (0.57) | IAPPLCKAPPCYP19A1TYR | |
| SCHEMBL1331519 | 0.80 | KDM4E (0.70) | LCKALOX15IGF1RKDM4EMAPT | |
| SCHEMBL29503757 | 0.80 | KDM4E (0.70) | LCKALOX15IGF1RKDM4EMAPT | |
| SCHEMBL3182462 | 0.80 | ALOX5 (0.70) | GAATDP1LMNAPOLBTSHR | |
| Didemethyltetrahydrocurcumin SCHEMBL6344877 | 0.78 | IAPP (0.73) | IAPPLCKAPPCYP19A1TYR | |
| SCHEMBL925636 | 0.78 | IAPP (0.62) | IAPPLCKAPPCYP19A1TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113679836-A | Targeted ZIF-8-polydopamine prodrug nanoparticle and preparation method and application thereof | 南通大学 | 2021-11-23 | — | — | CN | disclosed |