Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2879577 | 0.92 | GPR88 (0.33) | GPR88 | |
| SCHEMBL3811154 | 0.92 | TRPV1 (0.37) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL3809541 | 0.92 | TRPV1 (0.37) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL3811193 | 0.92 | TRPV1 (0.37) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL2878984 | 0.90 | TRPM8 (0.38) | IKBKBKDM4ENPC1MAPTRAB9A | |
| SCHEMBL3814842 | 0.88 | IKBKB (0.38) | IKBKBKDM4ENPC1MAPTRAB9A | |
| SCHEMBL2871046 | 0.87 | IKBKB (0.41) | IKBKBKDM4ENPC1MAPTRAB9A | |
| SCHEMBL2878950 | 0.87 | IKBKB (0.41) | IKBKBKDM4ENPC1MAPTRAB9A | |
| SCHEMBL6266218 | 0.87 | IKBKB (0.41) | IKBKBKDM4ENPC1MAPTRAB9A | |
| SCHEMBL3811209 | 0.83 | TRPV1 (0.37) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569929-B9 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2011-09-14 | — | — | EP | claimed |
| EP-1569929-B1 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2010-05-05 | — | — | EP | claimed |