Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Propionate SCHEMBL28742006 | 0.84 | PKM (0.38) | — | |
| SCHEMBL185155 | 0.82 | — | — | |
| SCHEMBL29936230 | 0.82 | — | — | |
| Trifluoroacetic Acid SCHEMBL30870503 | 0.81 | L3MBTL1 (0.31) | HCAR2 | |
| Hydrochloric Acid SCHEMBL30870490 | 0.80 | — | — | |
| SCHEMBL20695517 | 0.60 | GABRP (0.51) | KDM5BHCAR2 | |
| Propionic Acid SCHEMBL179975 | 0.60 | — | — | |
| Propionic Acid SCHEMBL8337137 | 0.60 | FFAR3 (0.91) | FFAR3ESR1 | |
| Pyridazine SCHEMBL27539151 | 0.59 | FFAR3 (0.56) | FFAR3 | |
| Indazole SCHEMBL23466993 | 0.59 | HSP90AA1 (0.63) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450006-A | TrkB positive allosteric modulators | 斯特拉斯堡大学 | 2022-05-06 | — | — | CN | disclosed |