Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL30870503

O=C(O)C(F)(F)F.c1cc2[nH]nnc2nn1

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL185155 0.82 — —
SCHEMBL29936230 0.82 — —
Propionic Acid SCHEMBL28741996 0.81 FFAR3 (0.32) HCAR2
Hydrochloric Acid SCHEMBL30870490 0.80 — —
Ethyl Propionate SCHEMBL28742006 0.72 PKM (0.38) —
Trifluoroacetic Acid SCHEMBL17893829 0.69 KMT2A (0.33) L3MBTL1HCAR2
Trifluoroacetic Acid SCHEMBL13822271 0.68 GPR6 (0.35) L3MBTL1
Trifluoroacetic Acid SCHEMBL4108467 0.66 MAPT (0.41) —
Trifluoroacetic Acid SCHEMBL15543969 0.65 CLK1 (0.41) L3MBTL1
Trifluoroacetic Acid SCHEMBL23457501 0.63 HCAR2 (0.35) HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260028347-A1 HETEROCYCLIC AND HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE PTC THERAPEUTICS INC (US) 2026-01-29 — — US disclosed
US-20240132509-A1 HETEROCYCLIC AND HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE PTC THERAPEUTICS INC (US) 2024-04-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028347-A1 HETEROCYCLIC AND HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE HTT, HYPK, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 L3MBTL1 1994/4885HCAR2 142/4885
US-20240132509-A1 HETEROCYCLIC AND HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE HTT, HCN3, TRPV1 L3MBTL1 3821/4885HCAR2 97/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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