Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | IDE | P14735 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | CASR | P41180 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2787298 | 1.00 | MEN1 (0.44) | MEN1KMT2AHPGDTRPV1NFE2L2 | |
| Hydrochloric Acid SCHEMBL2787295 | 0.99 | MEN1 (0.43) | MEN1KMT2AHPGDTRPV1NFE2L2 | |
| Hydrochloric Acid SCHEMBL2872916 | 0.99 | MEN1 (0.43) | MEN1KMT2AHPGDTRPV1NFE2L2 | |
| SCHEMBL15571660 | 0.84 | SIGMAR1 (0.51) | MEN1KMT2AHPGDADRA2CSLC6A2 | |
| SCHEMBL4730665 | 0.79 | MEN1 (0.53) | MEN1KMT2AHPGDTRPV1HTT | |
| SCHEMBL16212524 | 0.75 | ADRA2C (0.60) | MEN1KMT2AHPGDAPAF1IDE | |
| Hydrochloric Acid SCHEMBL1504932 | 0.74 | SIGMAR1 (0.60) | MEN1KMT2AHPGDAPAF1IDE | |
| SCHEMBL20921209 | 0.74 | RAB9A (0.49) | MEN1KMT2AHPGDNFE2L2HTT | |
| SCHEMBL1491268 | 0.74 | CASR (0.58) | MEN1KMT2ANFE2L2ADRA2CSLC6A2 | |
| SCHEMBL1331216 | 0.74 | CASR (0.58) | MEN1KMT2ANFE2L2ADRA2CSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2398763-A2 | PROCESS FOR PREPARING CINACALCET HYDROCHLORIDE | ZaCh System S.p.A. (IT) | 2011-12-28 | — | — | EP | disclosed |
| WO-2010094674-A2 | PROCESS FOR PREPARING CINACALCET HYDROCHLORIDE | ZACH SYSTEM S.P.A. (IT) | 2010-08-26 | — | — | WO | disclosed |