Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2874457 | 0.79 | MEN1 (0.44) | MEN1KMT2ALMNAMAPTNPSR1 | |
| SCHEMBL2787298 | 0.79 | MEN1 (0.44) | MEN1KMT2ALMNAMAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL2872916 | 0.78 | MEN1 (0.43) | MEN1KMT2ALMNATRPV1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL2787295 | 0.78 | MEN1 (0.43) | MEN1KMT2ALMNATRPV1L3MBTL1 | |
| SCHEMBL1491274 | 0.76 | NPC1 (0.56) | TRPV1HTTMTNR1A | |
| SCHEMBL31663470 | 0.76 | NPC1 (0.56) | TRPV1HTTMTNR1A | |
| SCHEMBL16071013 | 0.75 | MEN1 (0.64) | MEN1KMT2ALMNAHSP90AA1MAPT | |
| SCHEMBL2787141 | 0.74 | MTNR1A (0.47) | MEN1KMT2ALMNAHSP90AA1MAPT | |
| SCHEMBL6813373 | 0.74 | KDM4E (0.54) | MEN1KMT2ALMNAHSP90AA1MAPT | |
| SCHEMBL4732912 | 0.74 | KDM4E (0.54) | MEN1KMT2ALMNAHSP90AA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035381-A2 | PROCESS FOR THE PREPARATION OF AMINE DERIVATIVES AS CALCIMIMETICS | IND-SWIFT LABORATORIES LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |