SCHEMBL28746512

SCHEMBL28746512

CC(C)C(=O)N(C)c1cccc(I)c1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SCN2A Q99250 1/20 0.48
MLYCD O95822 1/20 0.43
USP30 Q70CQ3 2/20 0.41
HTR2C P28335 1/20 0.40
HTR6 P50406 1/20 0.40
MTNR1A P48039 1/20 0.36
MTNR1B P49286 1/20 0.36
APP P05067 1/20 0.36
HSD17B1 P14061 1/20 0.35
HSD17B2 P37059 1/20 0.35
HDAC1 Q13547 1/20 0.35
TACR1 P25103 1/20 0.34
LMNA P02545 1/20 0.34
HTR3E A5X5Y0 1/20 0.33
HTR3B O95264 1/20 0.33
HTR3A P46098 1/20 0.33
HTR3D Q70Z44 1/20 0.33
HTR3C Q8WXA8 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8276434 0.81 HSD17B1 (0.53) MLYCDUSP30HSD17B1HSD17B2LMNA
SCHEMBL2094143 0.80 SCN2A (0.51) SCN2AHTR2CHTR6APPHSD17B1
SCHEMBL2094148 0.80 SCN2A (0.51) SCN2AHTR2CHTR6APPHSD17B1
SCHEMBL3222780 0.79 SIGMAR1 (0.43) MLYCDUSP30HDAC1LMNAHTR3E
SCHEMBL17572209 0.78 MLYCD (0.56) MLYCDAPPHDAC1
SCHEMBL10962592 0.78 USP30 (0.51) MLYCDUSP30LMNAKMT2A
SCHEMBL30668615 0.78 USP30 (0.51) MLYCDUSP30LMNAKMT2A
SCHEMBL1139982 0.77 MLYCD (0.54) MLYCDHDAC1LMNAKMT2A
SCHEMBL14518797 0.77 HSD17B2 (0.57) MTNR1AMTNR1BHSD17B1HSD17B2
SCHEMBL1692195 0.77 SIGMAR1 (0.53)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114539121-A A novel, photo-promoted process for the preparation of sulfonates and sulfonamides from sulfonyl chlorides 天津师范大学 2022-05-27 CN disclosed