Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | PHGDH | O43175 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | LIPE | Q05469 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26644166 | 0.83 | KMT2A (0.46) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8586518 | 0.83 | KMT2A (0.46) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL26644163 | 0.83 | KMT2A (0.46) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL17775467 | 0.83 | HDAC1 (0.48) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7497496 | 0.83 | KMT2A (0.46) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL13831220 | 0.83 | KMT2A (0.46) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL28941358 | 0.82 | HDAC1 (0.50) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6672366 | 0.82 | MLYCD (0.54) | MLYCDKMT2APOLBHDAC1CA12 | |
| SCHEMBL1822378 | 0.82 | KMT2A (0.44) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL8010212 | 0.82 | KMT2A (0.44) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007094-A2 | ASTHMA AND ALLERGIC INFLAMMATION MODULATORS | TULARIK INC. (US) | 2005-01-27 | — | — | WO | claimed |
| JP-57144203-A | — | — | None | — | — | JP | disclosed |
| US-20230348369-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-11-02 | — | — | US | disclosed |
| US-20230348369-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-11-02 | — | — | US | disclosed |
| US-11744832-B2 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | INCYTE CORPORATION (US) | 2023-09-05 | — | — | US | disclosed |
| US-20230242514-A1 | BICYCLIC INDAZOLE GLUCOCORTICOID RECEPTOR ANTAGONISTS | CORCEPT THERAPEUTICS INCORPORATED | 2023-08-03 | — | — | US | disclosed |
| US-20230242514-A1 | BICYCLIC INDAZOLE GLUCOCORTICOID RECEPTOR ANTAGONISTS | CORCEPT THERAPEUTICS INCORPORATED | 2023-08-03 | — | — | US | disclosed |
| WO-2023077218-A1 | PHOTOCATALYSTS, PREPARATION AND USE THEREOF | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIVERSITY (CA) | 2023-05-11 | — | — | WO | disclosed |
| US-20220324866-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. | 2022-10-13 | — | — | US | disclosed |
| WO-2022166920-A1 | PYRROLOPYRIDAZINE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州中美华东制药有限公司 | 2022-08-11 | — | — | WO | disclosed |
| US-20030158412-A1 | Protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for the production and the use | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-08-21 | — | — | US | disclosed |
| US-6511991-B2 | Treating an amines with acetamidating agents to formacetamidine derivatives of the amine-containing compounds and treating the acetamidine derivatives with nitric oxide gas to form an amidine-derived diazeniumdiolate | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2003-01-28 | — | — | US | disclosed |
| US-20010025052-A1 | Novel nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions and uses thereof and method of making same | HRABIE JOSEPH A (US) | 2001-09-27 | — | — | US | disclosed |
| US-6232336-B1 | HYPOTENSIVE AGENTS; NEUROTRANSMISSION; CYTOTOXICITY | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2001-05-15 | — | — | US | disclosed |
| EP-1000023-A2 | NOVEL NITRIC OXIDE-RELEASING AMIDINE- AND ENAMINE-DERIVED DIAZENIUMDIOLATES, COMPOSITIONS AND USES THEREOF AND METHOD OF MAKING SAME | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, represented by THE DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999001427-A2 | NOVEL NITRIC OXIDE-RELEASING AMIDINE- AND ENAMINE-DERIVED DIAZENIUMDIOLATES, COMPOSITIONS AND USES THEREOF AND METHOD OF MAKING SAME | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH (US) | 1999-01-14 | — | — | WO | disclosed |
| US-4453975-A | WEED CONTROL IN CROPS; ESPECIALLY RICE | YASHIMA CHEMICAL INDUSTRIAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |
| EP-0061583-B1 | HERBICIDAL COMPOSITIONS CONTAINING ALPHA-ALPHA-DIMETHYL PHENYLACETANILIDES | YASHIMA CHEMICAL INDUSTRIAL CO., LTD. (JP) | 1984-05-02 | — | — | EP | disclosed |
| EP-0061583-A1 | Herbicidal compositions containing alpha-alpha-dimethyl phenylacetanilides | YASHIMA CHEMICAL INDUSTRIAL CO., LTD. (JP) | 1982-10-06 | — | — | EP | disclosed |
| JP-S57144203-A | HERBICIDE | YASHIMA CHEM IND CO LTD | 1982-09-06 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220324866-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | DGKG, DGKB, DGKK | MLYCD 1151/4885KMT2A 2566/4885CHRNB2 4159/4885 |
| US-20230348369-A1 | NAMPT MODULATORS | NAMPT, NNT, NAPRT | MLYCD 3451/4885KMT2A 1973/4885CHRNB2 2750/4885 |
| US-20030158412-A1 | Protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for the production and the use | DHPS, VARS1, CYP51A1 | MLYCD 199/4885KMT2A 1241/4885CHRNB2 4402/4885 |
| US-11744832-B2 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | JAK3, JAK1, JAK2 | MLYCD 2671/4885KMT2A 780/4885CHRNB2 4730/4885 |
| US-20230242514-A1 | BICYCLIC INDAZOLE GLUCOCORTICOID RECEPTOR ANTAGONISTS | NR3C1, NR3C2, NR1I2 | MLYCD 3519/4885KMT2A 4270/4885CHRNB2 198/4885 |
| US-20010025052-A1 | Novel nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions and uses thereof and method of making same | NOS2, NOS1, NOS3 | MLYCD 777/4885KMT2A 3662/4885CHRNB2 175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.