Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 2/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2867867 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KDM4EPKMDNM1MEN1 | |
| SCHEMBL2876635 | 0.80 | KDM4E (0.42) | ALDH1A1KDM4EPKMDNM1MEN1 | |
| SCHEMBL26297238 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4EPKMDNM1MEN1 | |
| SCHEMBL2875129 | 0.78 | USP2 (0.48) | ALDH1A1KDM4EPKMDNM1CA1 | |
| SCHEMBL2875724 | 0.77 | USP2 (0.47) | ALDH1A1KDM4EPKMDNM1MEN1 | |
| SCHEMBL2877517 | 0.76 | CHRNB2 (0.36) | ALDH1A1ACEMME | |
| SCHEMBL2624391 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KDM4EPKMDNM1MEN1 | |
| SCHEMBL2880181 | 0.74 | USP2 (0.59) | ALDH1A1KDM4EPKMDNM1CA1 | |
| SCHEMBL19407128 | 0.74 | KDM4E (0.40) | ALDH1A1KDM4EPKMDNM1MEN1 | |
| SCHEMBL2880160 | 0.74 | USP2 (0.44) | ALDH1A1KDM4EPKMDNM1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1570835-B1 | Composition for the permanent deformation of the hair comprising at least one carboxydithiol | OREAL (FR) | 2010-10-20 | — | — | EP | claimed |
| US-20050208007-A1 | Composition to permanently reshape the hair containing at least one carboxydithiol | L'OREAL S.A. (FR) | 2005-09-22 | — | — | US | claimed |
| EP-1570835-A1 | Composition for the permanent deformatioh of the hair comprising at least one carboxydithiol | L'OREAL (FR) | 2005-09-07 | — | — | EP | claimed |
| US-20050208007-A1 | Composition to permanently reshape the hair containing at least one carboxydithiol | L'OREAL S.A. (FR) | 2005-09-22 | — | — | US | disclosed |
| EP-1570835-A1 | Composition for the permanent deformatioh of the hair comprising at least one carboxydithiol | L'OREAL (FR) | 2005-09-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050208007-A1 | Composition to permanently reshape the hair containing at least one carboxydithiol | CTH, BHMT2, CRAT | ALDH1A1 390/4885KDM4E 604/4885PKM 4120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.