Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MMP13 | P45452 | 3/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28397208 | 1.00 | HSD11B1 (0.61) | HSD11B1ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL28397210 | 1.00 | HSD11B1 (0.61) | HSD11B1ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL12259812 | 0.92 | MMP13 (0.58) | HSD11B1MMP13MMP1HTTNPSR1 | |
| SCHEMBL28410589 | 0.87 | ALDH1A1 (0.54) | HSD11B1ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL12237259 | 0.87 | ALDH1A1 (0.54) | HSD11B1ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL28410587 | 0.87 | ALDH1A1 (0.54) | HSD11B1ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL12237262 | 0.85 | MMP13 (0.51) | HSD11B1ALDH1A1RAB9AMMP13MMP1 | |
| SCHEMBL12259813 | 0.85 | GAA (0.52) | HSD11B1ALDH1A1MMP13MMP1HTT | |
| SCHEMBL28748875 | 0.84 | L3MBTL1 (0.55) | HSD11B1AOC3L3MBTL1 | |
| SCHEMBL28748828 | 0.84 | L3MBTL1 (0.55) | HSD11B1AOC3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116769741-B | Fusion protein composition and synthesis method of double-enzyme immobilized PHA microsphere and beta-hydroxy sulfone | 河北牧群生物科技有限公司 | 2024-06-18 | — | — | CN | claimed |
| CN-116769741-A | Fusion protein composition and synthesis method of double-enzyme immobilized PHA microsphere and beta-hydroxy sulfone | 河北牧群生物科技有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-116769741-B | Fusion protein composition and synthesis method of double-enzyme immobilized PHA microsphere and beta-hydroxy sulfone | 河北牧群生物科技有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-114540321-B | Preparation method of R-2-sulfonyl-1-phenylethanol derivative | 沈阳药科大学 | 2024-04-02 | — | — | CN | disclosed |
| CN-116769741-A | Fusion protein composition and synthesis method of double-enzyme immobilized PHA microsphere and beta-hydroxy sulfone | 河北牧群生物科技有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-114540321-A | Preparation method of R-2-sulfonyl-1-phenylethanol derivative | 沈阳药科大学 | 2022-05-27 | — | — | CN | disclosed |