SCHEMBL28749909

SCHEMBL28749909

OCCc1ccc(OB(O)O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.48
PPARA Q07869 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
CYP4F2 P78329 4/20 0.41
CYP4A11 Q02928 4/20 0.41
HRH3 Q9Y5N1 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
TSHR P16473 1/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
ALOX5 P09917 1/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28119749 0.88 LTA4H (0.51) CA2PPARACYP4F2CYP4A11CA1
SCHEMBL1251529 0.82 LTA4H (0.50) CA2PPARAHRH3CA12CA1
SCHEMBL761972 0.81 LPL (0.55) CA2PPARACA1ALDH1A1
SCHEMBL29112149 0.81 TAAR1 (0.55) TDP1KDM4EALDH1A1BACE1
SCHEMBL27489645 0.81 TDP1 (0.43) CA2TDP1CA1CALM1
SCHEMBL7931146 0.79 ENPP2 (0.51) TDP1MAPTCALM1
SCHEMBL3800806 0.78 CA1 (0.38) CA2CA12CA1CA7CA9
SCHEMBL2773646 0.78 CA1 (0.58) CA2CA1KDM4EALDH1A1GAA
SCHEMBL2167811 0.77 CA2 (0.56) CA2PPARATDP1CYP4F2CYP4A11
SCHEMBL29618986 0.77 CA2 (0.56) CA2PPARATDP1CYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119192264-A 4-Hydroxymethylphenylboronic acid modified amphotericin B derivative and preparation method and application thereof 西南大学 2024-12-27 CN disclosed
CN-106146459-A A kind of preparation method of bilastine 山东罗欣药业集团恒欣药业有限公司 2016-11-23 CN disclosed
CN-1477960-A EPA receptor inhibitors to treat rheumatoid arthritis 2004-02-25 CN disclosed