Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | LOX | P28300 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | C1S | P09871 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18503869 | 0.85 | HTT (0.54) | KEAP1NFE2L2POLBPKMNPC1 | |
| SCHEMBL10002504 | 0.83 | NPC1 (0.54) | KEAP1NFE2L2POLBPKMNPC1 | |
| SCHEMBL1379068 | 0.80 | ALDH1A1 (0.48) | KEAP1NFE2L2POLBPKMNPC1 | |
| SCHEMBL4683020 | 0.79 | NFE2L2 (0.53) | KEAP1NFE2L2POLBPKMNPC1 | |
| SCHEMBL4004512 | 0.79 | NFE2L2 (0.53) | KEAP1NFE2L2POLBPKMNPC1 | |
| SCHEMBL18503870 | 0.79 | KEAP1 (0.54) | KEAP1NFE2L2POLBPKMNPC1 | |
| SCHEMBL4685420 | 0.78 | NFE2L2 (0.47) | KEAP1NFE2L2POLBPKMNPC1 | |
| Hydrochloric Acid SCHEMBL3510149 | 0.77 | NFE2L2 (0.51) | KEAP1NFE2L2POLBPKMNPC1 | |
| Hydrochloric Acid SCHEMBL3510733 | 0.77 | NFE2L2 (0.51) | KEAP1NFE2L2POLBPKMNPC1 | |
| SCHEMBL4683019 | 0.77 | NFE2L2 (0.58) | KEAP1NFE2L2POLBPKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1432059-A | Targeted moieties for use in blech catalysts | UNILEVER PLC (NL) | 2003-07-23 | — | — | CN | disclosed |