Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.34 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27612907 | 0.83 | — | — | |
| SCHEMBL27594326 | 0.83 | CYP3A4 (0.35) | GRM5 | |
| SCHEMBL27594351 | 0.79 | LMNA (0.34) | LMNAMAPTERN1 | |
| SCHEMBL27594327 | 0.76 | KDM4E (0.51) | RAB9AKDM4EALDH1A1MAPK1LMNA | |
| SCHEMBL27612886 | 0.76 | DYRK1A (0.51) | ALDH1A1CYP1A2CYP2A6CYP19A1ERN1 | |
| SCHEMBL27612839 | 0.76 | KDM4E (0.40) | RAB9AKDM4EALDH1A1MAPK1LMNA | |
| SCHEMBL27594463 | 0.76 | OPRD1 (0.40) | RAB9AKDM4EPIK3CDPIK3CAPI4KA | |
| SCHEMBL27612815 | 0.71 | ERN1 (0.31) | ERN1 | |
| SCHEMBL27612912 | 0.69 | KDM4E (0.36) | RAB9AKDM4EALDH1A1MAPK1PIK3CD | |
| SCHEMBL27612864 | 0.69 | KDM4E (0.40) | RAB9AKDM4EALDH1A1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585775-A | 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials | ORTHO MCNEIL PHARM INC (US) | 2005-02-23 | — | — | CN | disclosed |